Abstract We evaluated the prospective Single Belt Conversions association of mitochondrial DNA copy number (mtDNA CN) with markers of kidney function among a cohort of persons who inject drugs (PWID).This is a Prospective cohort study nested in the AIDS linked to the intravenous experience cohort (community-based cohort of PWID in Baltimore, MD).mt
Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
Infection with Orientia tsutsugamushi, an obligate intracellular bacterium, can cause mild or severe scrub typhus.Some patients develop acute lung injury, multi-organ failure, and fatal infection; however, little is known regarding key immune mediators that mediate infection control or disease pathogenesis.Using murine models of scrub typhus, we de
Morphological, phytochemical and molecular characterization of five common Jatropha species in the Niger Delta Region of Nigeria
The economic and medicinal important genus Jatropha contains many distinctly different species.To elucidate the genetic relationship of five common occurring Jatropha species namely J.multifida, J.podagrica, J.tanjorernsis, J.curcas, and J.gossypifolia, thirty-nine morphological, six phytochemical features and one arbitrary marker was used to scree
Keeping Abreast with long non-coding RNAs in mammary gland development and breast cancer
The majority of the human genome is transcribed, even though only 2% of transcripts encode proteins.Non-coding transcripts were originally dismissed as evolutionary junk or transcriptional noise, but with the development of whole genome technologies, these ncRNAs are emerging as molecules with vital roles in regulating gene expression.While shorter